Cyclobenzaprine has an average rating of 5.9 out of 10 from a total of 616 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 31% reported a negative effect. Naproxen has an average rating of 6.9 out of 10 from a total of 677 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 25% reported a negative
Letzel et al. investigated the efficacy and safety of aceclofenac 100 mg tablet against placebo and naproxen 500 mg tablets given orally . The evaluation of pain was carried out with a 10-point VAS scale. The patients who had a VAS score higher than 6 were accepted to the study.
Objective: To evaluate and compare the efficacy and tolerability of etoricoxib and diclofenac in patients with osteoarthritis of the knee or hip. Methods: In this 6-week double-blind, active comparator controlled, parallel-group study eligible osteoarthritis patients were randomised to receive either etoricoxib 60 mg once daily (n = 256) or diclofenac 50 mg three times daily (n = 260).
Here are the leraning points which suggest that taking anti-inflammatory medications was harmful than under going replacement surgery. Cause of patient death was highest for naproxen and lowest for total hip replacement. Highest gastrointestinal complications were reported for diclofenac and lowest for total knee replacement. FebpsEH.